Genetics of Human Infertility (Monographs in Human Genetics, Vol. 21) (PDF)

Genetics of Human Infertility (Monographs in Human Genetics, Vol. 21) (PDF)

by M. Schmid (Series Editor) and P.H. Vogt (Editor)_0

More than one in ten couples experience infertility , which is linked to a wide range of diseases that are occasionally only detectable in the germ line . In addition to anatomical problems, immunological interference and environmental factors , its complicated etiology frequently but not always includes genetic elements .

Only genetic problems are likely to blame for close to 30% of cases of infertility . Experimental animal knockout models therefore effectively demonstrate that single or several gene abnormalities may contribute to infertility . Because it is difficult to translate these fundamental research findings into clinical investigations , genetic explanations for the great majority of infertile patients remain unknown .

Nevertheless , highly advanced molecular techniques have identified a significant number of potential genes . This book offers a thorough overview of the topic of infertility prepared by the foremost experts in this area . Basic biological , cytological and molecular research are covered , along with common and rare disorders . Human geneticists , endocrinologists , epidemiologists , zoologists and counselors who work in the fields of human genetics , infertility and assisted reproduction should all study it .

See Also: Emery’s Elements of Medical Genetics, 15th Edition (PDF)