Sample Sizes for Clinical Trials , 2nd Edition (Original PDF from Publisher)

Sample Sizes for Clinical Trials , 2nd Edition (Original PDF from Publisher)

Author : Steven A. Julious

A useful book that aids researchers in their assessment of the sample size for clinical studies is Sample Sizes for Clinical Trials , Second Edition . The book is filled with thorough worked examples that demonstrate how to perform the calculations as well as how to communicate them to colleagues or in protocols . Along with outlining the crucial procedures that lead to the final sample size calculation, the book also points out several calculating mistakes.

Features :

complete sample size calculation coverage, including data on survival , binary , ordinal and normal outcomes . covers the following criteria for both parallel group and crossover designs: superiority , equivalence , non-inferiority , bioequivalence, and accuracy . demonstrates how trial objectives have an impact on the research design in terms of both the size of the study and the formulas used to derive the sample .

Inspired with illustrations of practical clinical trials demonstrating the use of the calculations . All chapters in the new version have been expanded , some significantly and four whole new chapters on multiplicity , cluster trials, pilot studies, and single arm trials have also been added .

The book , which might be used to teach a course on sample size calculations, is primarily intended for researchers and practitioners of clinical trials and biostatistics . The book emphasizes the significance of a sample size estimate while creating a clinical study . It allows users to rapidly locate a suitable sample size formula, along with a worked example and other tables to aid with the computations .

See Also : Visual Thinking : The Hidden Gifts of People Who Think in Pictures, Patterns, and Abstractions (EPUB)

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